Endocrine Abstracts

Normocalcaemic hyperparathyroidism (NPHPT) is characterised by persistently normal calcium levels and elevated PTH values on at least two consecutive measurements, after excluding other causes of secondary hyperparathyroidism. This group of patients is challenging to identify and characterise. The prevalence of the disease in the literature varies significantly due to the various definitions used and the fact that not all causes of secondary hyperparathyroidism have been exclu...

Introduction: Avascular necrosis of the femoral head (AVN) is most commonly a consequence of glucocorticoid excess and is believed to be due to osteocyte apoptosis. It can also be due to vascular occlusion or trauma. We describe a patient with congenital adrenal hyperplasia secondary to 17-hydroxylase deficiency who presented with osteoporotic vertebral fractures and atraumatic avascular necrosis of the femoral head. She was also found to have mild cardiomyopathy.<p class=...

Background: At the Metabolic Bone Centre in Sheffield, UK, patients with asymptomatic primary hyperparathyroidism (PHPT) are followed up annually through a register, with annual blood tests, questionnaires inquiring about symptoms or renal stones within the past year, and biennial DXA scans, which doctors then evaluate. Patients are recalled to the clinic if their reported symptoms and/or biochemical results suggest abnormalities associated with PHPT requiring...